{"id":47851,"date":"2024-04-23T14:03:41","date_gmt":"2024-04-23T06:03:41","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/47851"},"modified":"2024-04-23T14:03:41","modified_gmt":"2024-04-23T06:03:41","slug":"corticosterone","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/47851","title":{"rendered":"corticosterone","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-47850\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/04\/b49394cb38a54219a93683861a6d85ba-5.gif\" width=\"193\" height=\"134\" alt=\"Corticosterone structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>013A<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C21H30O4<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>346.46<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         corticosterone,<\/p>\n<p>                         adrenaline corticosterone,<\/p>\n<p>                         adrenaline,<\/p>\n<p>                         11\u03b2,21-Dihydroxy-4-pregnene-3,20-dione,<\/p>\n<p>                         11\u03b2,21-Dihydroxyprogesterone,<\/p>\n<p>                         4-Pregnene-11\u03b2,21-diol-3,20-dione,<\/p>\n<p>                         Kendall\u2019s Compound B,<\/p>\n<p>                         Reichstein&#8217;s Substance<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>50-22-6<\/p>\n<p><b>MDL number:<\/b>MFCD00037715<\/p>\n<p><b>EINECS number:<\/b>200-019-6<\/p>\n<p><b>RTECS number:<\/b>GM7650000<\/p>\n<p><b>BRN number:<\/b>2339601<\/p>\n<p><b>PubChem number:<\/b>24278302<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p><p>1. Properties: White crystalline powder, odorless, initially tasteless, then has a persistent bitter taste<\/p>\n<p>2. Density (g\/mL, 25\/4\u2103): Undetermined<\/p>\n<p>3. Relative vapor density (g\/mL, air=1): Undetermined<\/p>\n<p>4. Melting point (\u00baC): 179-183 \u00b0C (lit.)<\/p>\n<p>  5. Boiling point (\u00baC, normal pressure): Undetermined<\/p>\n<p>6. Boiling point (\u00baC, 5.2 kPa): Undetermined<\/p>\n<p>7. Refractive index: Undetermined<\/p>\n<p>8. Flash point (\u00baC): Undetermined<\/p>\n<p>9. Specific rotation (\u00ba): Undetermined<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC): Undetermined  Determined<\/p>\n<p>11. Vapor pressure (kPa, 25 \u00baC): Undetermined<\/p>\n<p>12. Saturated vapor pressure (kPa, 60 \u00baC): Undetermined<\/p>\n<p>13  . Heat of combustion (KJ\/mol): Undetermined<\/p>\n<p>14. Critical temperature (\u00baC): Undetermined<\/p>\n<p>15. Critical pressure (KPa): Undetermined<\/p>\n<p>16. Log value of oil-water (octanol\/water) partition coefficient: Undetermined<\/p>\n<p>17. Explosion upper limit (%, V\/V): Undetermined<\/p>\n<p>18. Explosion  Lower limit (%, V\/V): Undetermined<\/p>\n<p>19. Solubility: Easily soluble in methanol, ethanol, chloroform, slightly soluble in ether, benzene, acetone, not soluble in water, soluble in concentrated sulfuric acid  It turns into an orange-red solution with strong green fluorescence<\/p>\n<\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p><p>1. Molar refractive index: 94.03<\/p>\n<p>2. Molar volume (cm<sup>3<\/sup>\/mol): 284.0<\/p>\n<p>3. Isotonic specific volume (90.2K  ): 762.2<\/p>\n<p>4. Surface tension (dyne\/cm): 51.8<\/p>\n<p>5. Polarizability (10-24cm3)\ufffd\ufffd\ufffd37.27<\/p>\n<\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 2<\/p>\n<p>3. Number of hydrogen bond acceptors: 4<\/p>\n<p>4. Number of rotatable chemical bonds: 2<\/p>\n<p>5. Number of tautomers: 20<\/p>\n<p>6. Topological molecule polar surface area 74.6<\/p>\n<p>7. Number of heavy atoms: 25<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 638<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 7<\/p>\n<p>12. Uncertain number of atomic stereocenters: 0<\/p>\n<p>13. Determine the number of chemical bond stereocenters: 0  <\/p>\n<p>14. Number of uncertain chemical bond stereocenters: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p><p>This product should be sealed and stored in a dry place away from light.  <\/p>\n<\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p><p>It can be isolated from adrenal gland extract, or made from bile acid, yam saponin, etc.  <\/p>\n<\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p><p>An adrenocortical hormone.  It is used as an alternative treatment for adrenal insufficiency, but has serious side effects.  <\/p>\n<\/p>\n<p>     extended-reading:https:\/\/www.bdmaee.net\/nt-cat-a-4-catalyst-cas8001-28-0-newtopchem\/<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/40372<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44998<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44830<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/115<\/br>extended-reading:https:\/\/www.bdmaee.net\/dinbutyltindichloride\/<\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/dabco-ne500-non-emission-amine-catalyst-ne500\/<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/45056<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/44515<\/br>extended-reading:https:\/\/www.bdmaee.net\/dioctyl-tin-oxide-cas870-08-6-fascat-8201-catalyst\/<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 013A Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":47850,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15031],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47851"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=47851"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47851\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/47850"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=47851"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=47851"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=47851"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}