{"id":47858,"date":"2024-04-23T14:04:07","date_gmt":"2024-04-23T06:04:07","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/47858"},"modified":"2024-04-23T14:04:07","modified_gmt":"2024-04-23T06:04:07","slug":"vitamin-a","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/47858","title":{"rendered":"Vitamin A","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-47857\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/04\/1e510d82fea4405b8a01cad0580d4873-5.gif\" width=\"472\" height=\"227\" alt=\"Vitamin A structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>01F9<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C20H30O<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>286.5<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         2,4,6,8-nonatetraen-1-ol,<\/p>\n<p>                         All-trans-retinol,<\/p>\n<p>                         retinoid,<\/p>\n<p>                         Vitamin A alcohol,<\/p>\n<p>                         3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexane),<\/p>\n<p>                         A vitamin,<\/p>\n<p>                         Anti-xerophthalmia vitamins,<\/p>\n<p>                         3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol,<\/p>\n<p>                          all-trans-Retinol,<\/p>\n<p>                          Vitamin A1,<\/p>\n<p>                         Nutrition supplements,<\/p>\n<p>                         alcohol solvent<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>68-26-8<\/p>\n<p><b>MDL number:<\/b>MFCD00001552<\/p>\n<p><b>EINECS number:<\/b>200-683-7<\/p>\n<p><b>RTECS number:<\/b>VH6750000<\/p>\n<p><b>BRN number:<\/b>403040<\/p>\n<p><b>PubChem number:<\/b>24899395<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p><p>1. Character: faded flake crystal.<\/p>\n<p>2. Density (g\/mL, 20\/4\u2103): 0.954<\/p>\n<p>3. Relative vapor density (g\/  mL, air=1): Uncertain<\/p>\n<p>4. Melting point (\u00baC): 63.5<\/p>\n<p>5. Boiling point (\u00baC, normal pressure): 137, (0.00013pa)<\/p>\n<p>6. Boiling point (\u00baC, 0.667Pa): 120-125<\/p>\n<p>7. Refractive index: 1.641<\/p>\n<p>8. Flash point (\u00baC): -26<\/p>\n<p>9. Specific rotation (\u00ba): Uncertain<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC): Uncertain<\/p>\n<p>11. Vapor pressure (kPa,  25\u00baC): Uncertain<\/p>\n<p>12. Saturated vapor pressure (kPa, 60\u00baC): Uncertain<\/p>\n<p>13. Heat of combustion (KJ\/mol): Uncertain<\/p>\n<p>14. Critical temperature (\u00baC): Uncertain<\/p>\n<p>15. Critical pressure (KPa): Uncertain<\/p>\n<p>16. Log value of oil-water (octanol\/water) partition coefficient:  Uncertain<\/p>\n<p>17. Explosion upper limit (%, V\/V): Uncertain<\/p>\n<p>18. Explosion lower limit (%, V\/V): Uncertain<\/p>\n<p>19. Solubility: Soluble in absolute ethanol, methanol, chloroform, ether, fats and oils, almost insoluble in water or glycerol.<\/p>\n<\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p><p>1. Molar refractive index: 95.49<\/p>\n<p>2. Molar volume (cm<sup>3<\/sup>\/mol): 300.0<\/p>\n<p>3. \ufffd\ufffd\ufffd Zhang specific volume (90.2K): 738.0 <\/p>\n<p>4. Surface tension (dyne\/cm): 36.6<\/p>\n<p>5. Polarizability (10-24cm3): 37.85<\/p>\n<\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 1<\/p>\n<p>3. Number of hydrogen bond acceptors: 1<\/p>\n<p>4. Number of rotatable chemical bonds: 5<\/p>\n<p>5. Number of tautomers: none<\/p>\n<p>6. Topological molecule polar surface area 20.2<\/p>\n<p>7. Number of heavy atoms: 21<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 496<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 0<\/p>\n<p>12. Uncertain number of atomic stereocenters: 0<\/p>\n<p>13. Determine the number of chemical bond stereocenters: 4  <\/p>\n<p>14. Number of uncertain chemical bond stereocenters: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     1. Exist in tobacco leaves.\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p><p>This product should be sealed and stored in a cool, dry place away from light.  <\/p>\n<\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p><p>1. Natural vitamin A is extracted from cod liver oil.  Among them, retinol (vitamin A1) is extracted from the liver of marine fish, and 3-dehydroretinol (vitamin A2) is extracted from the liver of freshwater fish.  <\/p>\n<p>2. There are many artificial synthesis routes for retinol and its derivatives. The most common one is the Isler route, which is C13-C14-C20.  <\/p>\n<p>3.<span style=\"font-family:Arial\">Firstly, \u03b2\ue011ionone and ethyl monochloroacetate are condensed, and then hydrolyzed and decarboxylated to obtain tetradecanaldehyde; in addition, acetylene is obtained  Sodium is condensed with methylketene, and the resulting material reacts with ethylmagnesium bromide to obtain magnesium bromide.  Condensation, hydrolysis, and catalytic hydrogenation of magnesium dibromide with tetradecane aldehyde produce hydroxyvitamin A, react with acetyl chloride to obtain hydroxyvitamin acetate, and then brominate and debrominate to obtain vitamin acetate.  <\/span><\/p>\n<\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p><p>1. It can maintain vision and promote bone growth, maintain the integrity and soundness of epithelial structure, prevent night blindness, improve vision, maintain strong teeth, promote bone growth, promote children&#8217;s growth, keep skin moist, ensure normal hair growth, and enhance resistance.  force.  <\/p>\n<p>2.<span style=\"font-family:Arial\">Vitamin A is a component of the photosensitive substances in visual cells. Lysine is an essential amino acid for the human body and can maintain the integrity of the epithelial tissue structure.  and health, promoting the growth and development of the body.  When lacking, growth and development will be hindered and reproductive function will decline.  It is often used to prevent and treat children&#8217;s stunting, dry eye syndrome, night blindness, dry skin, and reduced resistance to infection in the eyes, respiratory tract, urinary system, and intestines.  Our country stipulates that it can be used in salad oil, sesame oil and margarine, and the usage amount is 4.0~8.0mg\/kg<\/span>; the maximum usage amount in solid beverages is 4~8  <span style=\"font-family:Arial\">mg\/kg<\/span>; the usage amount in baby food and dairy products is 3.0~9.0<span style=\"font-family:Arial\">mg\/kg  <\/span>; The maximum usage amount in ice cream is 0.6~1.2<span style=\"font-family:Arial\">mg\/kg<\/span>; The maximum usage amount in milk drinks is 0.61.0<span style=\"font-family:Arial\">mg\/kg<\/span>.  When \u03b2-carotene is used to fortify \u03b2-carotene beverages, the maximum usage amount is 20 to 40 mg\/kg; in solid beverages, the maximum usage amount is  3\uff5e5<span style=\"font-family:Arial\">mg\/kg<\/span>.  <\/span><\/p>\n<p>3.<span style=\"font-family:Arial\">Vitamin A is a component of the photosensitive substances in visual cells, which can ensure the integrity and health of the epithelial tissue structure and promote the body&#8217;s  development and growth.  When lacking, growth and development will be hindered and reproductive function will decline.  Retinyl acetate is generally added to feed.  <\/span><\/p>\n<p>4.<span style=\"font-family:Arial\">Nutritional supplements.  It is used as a nutrient additive in cosmetics to prevent rough skin and promote normal growth and development. It can be used in creams and lotions.  <\/span><\/p>\n<\/p>\n<p>     extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/New-generation-sponge-hardener.pdf<\/br>extended-reading:https:\/\/www.bdmaee.net\/polyurethane-sealer-ba100-delayed-catalyst-ba100-polyurethane-sealing-agent\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/chloriddi-n-butylcinicity\/<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/40495<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/708<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/175<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/45142<\/br>extended-reading:https:\/\/www.bdmaee.net\/bdma\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/tib-kat-129-3\/<\/br>extended-reading:https:\/\/www.cyclohexylamine.net\/catalyst-1027-polyurethane-catalyst-1027\/<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 01F9 Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":47857,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[1753],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47858"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=47858"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47858\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/47857"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=47858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=47858"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=47858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}