{"id":47881,"date":"2024-04-23T15:02:43","date_gmt":"2024-04-23T07:02:43","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/47881"},"modified":"2024-04-23T15:02:43","modified_gmt":"2024-04-23T07:02:43","slug":"miparin-dihydrochloride","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/47881","title":{"rendered":"Miparin dihydrochloride","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-47880\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/04\/dfe4b01817b241f09036a13a558c9a61-1.gif\" width=\"380\" height=\"227\" alt=\"Mipaline dihydrochloride structural formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>01FH<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C23H32Cl3N3O<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>472.88<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         malaria flat,<\/p>\n<p>                         Quinacine dihydrochloride,<\/p>\n<p>                         malaria diping,<\/p>\n<p>                         Miparin hydrochloride,<\/p>\n<p>                         Adipine dihydrochloride,<\/p>\n<p>                         Quinacine dihydrochloride,<\/p>\n<p>                         Quinacrine<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>69-05-6<\/p>\n<p><b>MDL number:<\/b>MFCD00012659<\/p>\n<p><b>EINECS number:<\/b>200-700-8<\/p>\n<p><b>RTECS number:<\/b>AR7875000<\/p>\n<p><b>BRN number:<\/b>4834013<\/p>\n<p><b>PubChem number:<\/b>24278192<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN> <\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>1.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Characteristics: bright yellow  Crystalline powder.  Odorless.  Bitter taste.  Hygroscopic.  Sensitive to light.  <\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>2.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Density (<\/SPAN><SPAN>g\/mL,25\/4<\/SPAN><SPAN>  \u2103): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>3.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Relative vapor density (  <\/SPAN><SPAN>g\/mL,<\/SPAN><SPAN>Air  <\/SPAN><SPAN>=1<\/SPAN><SPAN>): Not  OK<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>4.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Melting point (<\/SPAN><SPAN>\u00baC<\/SPAN><SPAN>):<\/SPAN>  <SPAN>248<\/SPAN><SPAN>\uff5e<\/SPAN><SPAN>250<\/SPAN><SPAN>\u2103 (decomposition)<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>5.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Boiling point (<\/SPAN><SPAN>\u00baC,<\/SPAN><SPAN>Normal pressure): Not  OK<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>6.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Boiling point (<\/SPAN><SPAN>\u00baC,5.2kPa<\/SPAN><SPAN>): Not  OK<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>7.<SPAN>\u00a0\u00a0\u00a0<\/SPAN><\/SPAN><\/SPAN><SPAN>Refractive index: Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>8.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Flashpoint (<\/SPAN><SPAN>\u00baC<\/SPAN><SPAN>): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>9.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Specific optical rotation (  <\/SPAN><SPAN>\u00ba<\/SPAN><SPAN>): Undetermined  <\/SPAN><SPAN><\/SPAN>  <\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>10.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Spontaneous ignition point or ignition  Combustion temperature (<\/SPAN><SPAN>\u00baC<\/SPAN><SPAN>)  : Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>11.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Vapor pressure (<\/SPAN><SPAN>kPa,25\u00baC<\/SPAN><SPAN>): Not  OK<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>12.<SPAN> &nbsp; <\/SPAN><\/SPAN><\/SPAN><SPAN>Saturated vapor pressure (<\/SPAN><SPAN>kPa,60\u00baC<\/SPAN><SPAN>): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>13.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Heat of combustion (<\/SPAN><SPAN>KJ\/mol<\/SPAN><SPAN>): Not  OK<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>14.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Critical temperature (<\/SPAN><SPAN>\u00baC<\/SPAN><SPAN>): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>15.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Critical pressure (<\/SPAN><SPAN>KPa<\/SPAN><SPAN>): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>16.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Oil and water (octanol  <\/SPAN><SPAN>\/<\/SPAN><SPAN>Water) distribution coefficient  The logarithmic value of : undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>17.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Explosion upper limit (<\/SPAN><SPAN>%,V\/V<\/SPAN><SPAN>): Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>18.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Lower explosion limit (<\/SPAN><SPAN>%,V\/V<\/SPAN><SPAN>)  : Undetermined<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>19.<SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Solubility: <\/SPAN><SPAN>1g<\/SPAN><SPAN>Product dissolves in approx.<\/SPAN><SPAN>35ml<\/SPAN><SPAN>Water, more soluble  In hot water, slightly soluble in ethanol and methanol, insoluble in ether, benzene and acetone.  <\/SPAN><SPAN>1%<\/SPAN><SPAN>Aqueous solution<\/SPAN><SPAN>pH<\/SPAN><SPAN>approximately<\/SPAN><SPAN>4.5<\/SPAN><SPAN>.  Under ultraviolet light, the yellow aqueous solution can display bright fluorescence.  <\/SPAN><SPAN> <\/SPAN>  <\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><\/SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"> <\/P>\n     <\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>1. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Number of hydrogen bond donors:<\/SPAN><SPAN>3<\/SPAN><SPAN>  <\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>2. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Hydrogen Bonding  Number of receptors: <\/SPAN><SPAN>4<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>3. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Rotatable  Number of chemical bonds: <\/SPAN><SPAN>9<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>4. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Interchange  Number of isomers: <\/SPAN><SPAN>2<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>5. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Topological molecules  Polar surface area (<\/SPAN><SPAN>TPSA<\/SPAN><SPAN>\uff09\uff1a<\/SPAN><SPAN>37.4<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>6. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Heavy atoms  Quantity: <\/SPAN><SPAN>30<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>7. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Surface charge:<\/SPAN><SPAN>0<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>8. <SPAN> <\/SPAN><\/SPAN><\/SPAN>  <SPAN>Complexity  \uff1a<\/SPAN><SPAN>461<\/SPAN><SPAN><\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>9. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Isotope atomic number:<\/SPAN><SPAN>0<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>10. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Determine the number of atomic stereocenters:<\/SPAN><SPAN>0<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>11. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Uncertain number of atomic stereocenters:<\/SPAN><SPAN>1<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>12. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Determine the number of stereocenters of chemical bonds:<\/SPAN><SPAN>0<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>13. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Uncertain number of chemical bond stereocenters:<\/SPAN><SPAN>0<\/SPAN><\/P><br \/>\n <P class=\"MsoNormal\" align=\"left\"><SPAN><SPAN>14. <SPAN> <\/SPAN><\/SPAN><\/SPAN><SPAN>Number of covalent bond units:<\/SPAN>  <SPAN>3<\/SPAN><\/P>\n     <\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p>\n     <P class=\"MsoNormal\" align=\"left\"><SPAN>This product should be sealed, dry and protected from light.  <\/SPAN><SPAN><\/SPAN><\/P>\n     <\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p>\n     <SPAN><SPAN> <\/SPAN><\/SPAN><SPAN>Organic synthesis.  Biochemical research.  For microscope use.  Pharmaceutical antimalarial and antiparasitic drugs.  <\/SPAN><SPAN><SPAN> <\/SPAN><SPAN> <\/SPAN><\/SPAN>\n     <\/p>\n<p>     extended-reading:https:\/\/www.bdmaee.net\/polyurethane-catalyst-smp\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/acetic-acid-potassium-salt\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/u-cat-3513n-catalyst-cas135083-58-9-sanyo-japan\/<\/br>extended-reading:https:\/\/www.bdmaee.net\/polycat-77-catalyst-cas3855-32-1-evonik-germany\/<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/535<\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/DBU-octoate&#8211;SA102-Niax-A-577.pdf<\/br>extended-reading:https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/66.jpg<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/1824<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/40016<\/br>extended-reading:https:\/\/www.newtopchem.com\/archives\/1148<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 01FH Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":47880,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15044],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47881"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=47881"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/47881\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/47880"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=47881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=47881"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=47881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}