{"id":49226,"date":"2024-05-27T16:29:48","date_gmt":"2024-05-27T08:29:48","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/49226"},"modified":"2024-05-27T16:29:48","modified_gmt":"2024-05-27T08:29:48","slug":"acetylsamine","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/49226","title":{"rendered":"acetylsamine","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-49225\" src=\"http:\/\/www.newtopchem.com\/wp-content\/uploads\/2024\/05\/69bc726bb27a45f1850920b3e4f45e06.gif\" width=\"241\" height=\"227\" alt=\"Acetylarsine Structural Formula\" \/><\/p>\n<p>Structural formula<\/p>\n<table class=\"summary-table table table-striped table-bordered\">\n<col width=\"90\" \/>\n<tbody>\n<tr>\n<th scope=\"row\">Business number<\/th>\n<td>02C6<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular formula<\/th>\n<td>C8H10AsNO5<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">Molecular weight<\/th>\n<td>275.09<\/td>\n<\/tr>\n<tr>\n<th scope=\"row\">label<\/th>\n<td>\n<p>                         acetapine,<\/p>\n<p>                         3-acetamido-4-hydroxyphenylarsonic acid,<\/p>\n<p>                         acetylsamine,<\/p>\n<p>                         Acetaminophen Hydroxybenzoic Acid,<\/p>\n<p>                         Acetamide arsine,<\/p>\n<p>                         N-Acetyl-4-hydroxy-m-arsanilic acid,<\/p>\n<p>                         [3-(Acetylamino)-4-hydroxyphenyl)]arsonic acid,<\/p>\n<p>                         Acetphenarsine<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<ul class=\"nav nav-tabs\">\n<li class=\"active\"><a href=\"#bh\">Numbering system<\/a><\/li>\n<li><a href=\"#wx\">Physical property data<\/a><\/li>\n<li><a href=\"#dl\">Toxicological data<\/a><\/li>\n<li><a href=\"#st\">Ecological data<\/a><\/li>\n<li><a href=\"#fz\">Molecular structure data<\/a><\/li>\n<li><a href=\"#js\">Computing chemical data<\/a><\/li>\n<li class=\"dropdown pull-right\">\n                     <a href=\"\" class=\"dropdown-toggle\">More <span class=\"caret\"><\/span><\/a><\/p>\n<ul class=\"dropdown-menu\" role=\"menu\">\n<li><a href=\"#xz\">Properties and Stability<\/a><\/li>\n<li><a href=\"#zc\">Storage method<\/a><\/li>\n<li><a href=\"#hc\">Synthesis method<\/a><\/li>\n<li><a href=\"#yt\">Purpose<\/a><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 id=\"bh\">Numbering system<\/h2>\n<p><b>CAS number:<\/b>97-44-9<\/p>\n<p><b>MDL number:<\/b>MFCD00019936<\/p>\n<p><b>EINECS number:<\/b>202-582-3<\/p>\n<p><b>RTECS number:<\/b>CF8400000<\/p>\n<p><b>BRN number:<\/b>None<\/p>\n<p><b>PubChem number:<\/b>24890414<\/p>\n<h2 id=\"wx\">Physical property data<\/h2>\n<p><p>1. Properties: White prismatic crystals, odorless.  <\/p>\n<p>2. Density (g\/mL, 20\u2103): Undetermined<\/p>\n<p>3. Relative vapor density (g\/mL, air=1): Undetermined<\/p>\n<p>4. Melting point (\u00baC): 240-250\u2103 (decomposition)<\/p>\n<p>5. Boiling point (\u00baC, normal pressure): Undetermined<\/p>\n<p>6. Boiling point (\u00baC, KPa)  : Undetermined<\/p>\n<p>7. Refractive index: Undetermined<\/p>\n<p>8. Flash point (\u00baC): Undetermined<\/p>\n<p>9. Specific rotation (\u00ba):  Not determined<\/p>\n<p>10. Autoignition point or ignition temperature (\u00baC): Not determined<\/p>\n<p>11. Vapor pressure (mmHg, 20.2\u00baC): Not determined<\/p>\n<p>  12. Saturated vapor pressure (kPa, \u00baC): Undetermined<\/p>\n<p>13. Heat of combustion (KJ\/mol): Undetermined<\/p>\n<p>14. Critical temperature (\u00baC): Undetermined<\/p>\n<p>15. Critical pressure (KPa): Undetermined<\/p>\n<p>16. Log value of oil-water (octanol\/water) partition coefficient: Undetermined<\/p>\n<p>17. Explosion  Upper limit (%, V\/V): Undetermined<\/p>\n<p>18. Lower explosion limit (%, V\/V): Undetermined<\/p>\n<p>19. Solubility: Slightly soluble in cold water and ethanol  and dilute acids, soluble in boiling water, caustic alkali solutions or carbonic acid alkali solutions.  <\/p>\n<\/p>\n<h2 id=\"dl\">Toxicological data<\/h2>\n<p>\n     Rat oral LD<sub>50<\/sub> is 4mg\/kg\n     <\/p>\n<h2 id=\"st\">Ecological data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"fz\">Molecular structure data<\/h2>\n<p>\n     None\n     <\/p>\n<h2 id=\"js\">Compute chemical data<\/h2>\n<p><p>1. Reference value for hydrophobic parameter calculation (XlogP): None<\/P><\/p>\n<p>2. Number of hydrogen bond donors: 4<\/p>\n<p>3. Number of hydrogen bond acceptors: 5<\/p>\n<p>4. Number of rotatable chemical bonds: 2<\/p>\n<p>5. Number of tautomers: 10<\/p>\n<p>6. Topological molecule polar surface area 107<\/p>\n<p>7. Number of heavy atoms: 15<\/p>\n<p>8. Surface charge: 0<\/p>\n<p>9. Complexity: 289<\/p>\n<p>10. Number of isotope atoms: 0<\/p>\n<p>11. Determine the number of atomic stereocenters: 0<\/p>\n<p>12. Uncertain.Number of \ufffd\ufffdstereocenters: 0<\/p>\n<p>13. Determine the number of stereocenters of chemical bonds: 0<\/p>\n<p>14. Uncertain number of stereocenters of chemical bonds: 0<\/p>\n<p>15. Number of covalent bond units: 1<\/p>\n<\/p>\n<h2 id=\"xz\">Properties and stability<\/h2>\n<p>\n     1. Highly toxic.\n     <\/p>\n<h2 id=\"zc\">Storage method<\/h2>\n<p><p>Stored sealed and protected from light.  <\/p>\n<\/p>\n<h2 id=\"hc\">Synthesis method<\/h2>\n<p><p>Originated from acetylation of 1.3-amino-4-hydroxyphenylarsonic acid.  Add 3-amino-4-hydroxyphenylarsonic acid to 5% sodium hydroxide solution and stir until completely dissolved.  Adjust pH to 8, heat to 30-35\u00b0C, add acetic anhydride under vigorous stirring to precipitate, continue stirring for 1 hour, add hydrochloric acid at 55-60\u00b0C to precipitate crystals, filter, and wash with water to obtain crude acetylsamine.  Refining: Dissolve the crude product in 5% sodium hydroxide solution, add activated carbon, stir, filter, and slowly add 10% sulfuric acid to the filtrate to make the Congo red test paper turn blue and precipitate crystals.  Filter and wash to obtain refined acetylsamine.  <\/p>\n<\/p>\n<h2 id=\"yt\">Purpose<\/h2>\n<p><p>1. Medicine.  Disinfectant, has the effect of killing trichomoniasis, and is used to treat vaginal trichomoniasis.  It is often made into Diweijing tablets, each tablet contains 0.25g of acetylsamine and 0.30g of boric acid.  <\/p>\n<\/p>\n<p>     extended-reading:<a href=\"https:\/\/www.bdmaee.net\/cas23850-94-4\/\">https:\/\/www.bdmaee.net\/cas23850-94-4\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44031\">https:\/\/www.newtopchem.com\/archives\/44031<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/nn-dicyclohexylmethylamine\/\">https:\/\/www.bdmaee.net\/nn-dicyclohexylmethylamine\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/39847\">https:\/\/www.newtopchem.com\/archives\/39847<\/a><\/br>extended-reading:<a href=\"https:\/\/www.bdmaee.net\/niax-a-33-catalyst-momentive\/\">https:\/\/www.bdmaee.net\/niax-a-33-catalyst-momentive\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/pc-cat-np109-low-odor-tertiary-amine-catalyst-polycat-9\/\">https:\/\/www.cyclohexylamine.net\/pc-cat-np109-low-odor-tertiary-amine-catalyst-polycat-9\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/45117\">https:\/\/www.newtopchem.com\/archives\/45117<\/a><\/br>extended-reading:<a href=\"https:\/\/www.morpholine.org\/delayed-catalyst-for-foaming-dabco-dc2-polyurethane-catalyst-dabco-dc2\/\">https:\/\/www.morpholine.org\/delayed-catalyst-for-foaming-dabco-dc2-polyurethane-catalyst-dabco-dc2\/<\/a><\/br>extended-reading:<a href=\"https:\/\/www.newtopchem.com\/archives\/44515\">https:\/\/www.newtopchem.com\/archives\/44515<\/a><\/br>extended-reading:<a href=\"https:\/\/www.cyclohexylamine.net\/high-quality-cas-136-53-8-zinc-octoate-ethylhexanoic-acid-zinc-salt\/\">https:\/\/www.cyclohexylamine.net\/high-quality-cas-136-53-8-zinc-octoate-ethylhexanoic-acid-zinc-salt\/<\/a><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"<p>Structural formula Business number 02C6 Molecular formu&#8230;<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":49225,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[15417],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49226"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=49226"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/49226\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media\/49225"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=49226"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=49226"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=49226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}