{"id":56213,"date":"2025-03-12T18:58:23","date_gmt":"2025-03-12T10:58:23","guid":{"rendered":"http:\/\/www.newtopchem.com\/archives\/56213"},"modified":"2025-03-12T18:58:23","modified_gmt":"2025-03-12T10:58:23","slug":"dimethylcyclohexylamine-dmcha-a-new-catalytic-technology-from-the-perspective-of-green-chemistry","status":"publish","type":"post","link":"http:\/\/www.newtopchem.com\/archives\/56213","title":{"rendered":"Dimethylcyclohexylamine (DMCHA): A new catalytic technology from the perspective of green chemistry","gt_translate_keys":[{"key":"rendered","format":"text"}]},"content":{"rendered":"

Dimethylcyclohexylamine (DMCHA): a new catalytic technology from the perspective of green chemistry<\/h1>\n

Foreword: From “behind the scenes” to “star elements”<\/h2>\n

In the world of chemistry, there is such a type of molecules that do not always stand in the spotlight, but silently push the forward of industry. They are the best among catalysts, additives and reaction promoters, and dimethylcyclohexylamine (DMCHA) is one of them. DMCHA, a seemingly ordinary organic compound, has gradually emerged in the field of green chemistry due to its unique structure and properties, and has become an indispensable member of modern catalytic technology. <\/p>\n

As a member of the cyclohexylamine family, the molecular structure of DMCHA is like a delicate bridge, cleverly connecting two methyl groups and one cyclohexyl group. This structure gives it excellent alkalinity, solubility and catalytic activity, making it play a key role in many chemical reactions. However, the charm of DMCHA is much more than that. With increasing global attention to sustainable development and environmental protection, DMCHA has become one of the focus in green chemistry research with its low toxicity and high selectivity. Its applications range from plastic manufacturing to coating curing to pharmaceutical intermediate synthesis, covering almost every aspect of modern industry. <\/p>\n

This article will use easy-to-understand language and combined with humorous rhetorical techniques to comprehensively analyze the properties, preparation methods, application fields and its development potential from the perspective of green chemistry. We will also organize relevant parameters in the form of a table, and refer to authoritative domestic and foreign literature to deeply explore how DMCHA plays an important role in new catalytic technology. If you are interested in chemistry or want to learn how to solve industrial problems in a more environmentally friendly way, this article is definitely worth reading! <\/p>\n

Next, let us enter the world of DMCHA together and unveil its mystery! <\/p>\n

\n

The basic characteristics of DMCHA: molecular structure and physicochemical properties<\/h2>\n

Molecular structure: a display of chemical “architecture”<\/h3>\n

DMCHA has a molecular formula of C8H17N, and its structure can be regarded as a chemical building composed of three main “building modules”: two active methyl groups (-CH3), a stable six-membered cyclohexyl group (C6H11), and a nitrogen atom (N). The nitrogen atom plays a crucial role in this edifice – it not only provides the alkalinity of the molecules, but also acts as the “commander” in the reaction process, guiding other molecules to react in predetermined paths. <\/p>\n

From the three-dimensional space perspective, the cyclohexyl part of DMCHA exhibits a chair-like conformation, which makes the molecules have high stability. The two methyl groups are located on both sides of the ring, giving the entire molecule a certain asymmetry. This special structural design is like a skillThe key created by the heart can accurately open certain specific chemical reaction locks. <\/p>\n\n\n\n\n\n\n\n
parameter name<\/th>\nSymbol<\/th>\nvalue<\/th>\n<\/tr>\n
Molecular Weight<\/td>\nMw<\/td>\n127.23 g\/mol<\/td>\n<\/tr>\n
Boiling point<\/td>\nTb<\/td>\n190\u00b0C<\/td>\n<\/tr>\n
Melting point<\/td>\nTm<\/td>\n-15\u00b0C<\/td>\n<\/tr>\n
Density<\/td>\n\u03c1<\/td>\n0.85 g\/cm\u00b3<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Physical and chemical properties: a versatile “chemistry artist”<\/h3>\n

DMCHA’s physical and chemical properties are colorful, as if it is an artist with unique skills who can show his talents on different stages. <\/p>\n

1. Alkaline<\/strong><\/h4>\n

The basicity of DMCHA is derived from the nitrogen atoms in its molecules. In solution, DMCHA can release hydroxide ions (OH\u207b), thus showing significant alkalinity. This alkalinity allows DMCHA to show its strength in acid-base catalytic reactions. For example, in the esterification reaction, amidation reaction and epoxy resin curing process, DMCHA can effectively promote the progress of the reaction. <\/p>\n

2. Solution<\/strong><\/h4>\n

DMCHA has good solubility, is both soluble in water and can shuttle freely in most organic solvents. This biabi capability allows it to easily adapt to various reaction conditions, whether it is the aqueous phase or the organic phase, DMCHA can complete tasks with ease. <\/p>\n

3. Volatility<\/strong><\/h4>\n

The boiling point of DMCHA is 190\u00b0C, which indicates that it is relatively stable at room temperature but gradually evaporates when heated. This characteristic is particularly important for processes that require control of reaction rates, as the degree of participation of DMCHA can be precisely regulated by adjusting the temperature. <\/p>\n

4. Toxicity<\/strong><\/h4>\n

Compared with traditional organic amine compounds, DMCHA has lower toxicity. This feature makes it safer and more reliable in industrial applications and is in line with the core concept of green chemistry – reducing negative impacts on the environment and human health. <\/p>\n\n\n\n\n\n\n\n
Properties<\/th>\nScanDescription<\/th>\n<\/tr>\n
Alkaline<\/td>\n Strongly alkaline, suitable for acid-base catalysis<\/td>\n<\/tr>\n
Solution<\/td>\nSoluble in water and a variety of organic solvents<\/td>\n<\/tr>\n
Volatility<\/td>\nMedium volatile, significantly affected by temperature<\/td>\n<\/tr>\n
Toxicity<\/td>\nLower toxicity, meets green chemistry requirements<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Funny interpretation: DMCHA’s personality portrait<\/h3>\n

If DMCHA is compared to a person, it must be a “chemistry expert” with a distinct personality. It has both a rigorous side and can accurately control reaction conditions; it also has a flexible side that can easily adapt to different environments. It is like an experienced mentor who can always lead other molecules to successfully complete complex chemistry tasks. At the same time, it also pays great attention to environmental protection and always aims at low energy consumption and small pollution, making it a “green pioneer” in the chemistry industry. <\/p>\n

\n

DMCHA preparation method: from laboratory to industrialization<\/h2>\n

The preparation methods of DMCHA are diverse, and each method has its own unique advantages and disadvantages. Depending on actual demand and production scale, you can choose the appropriate process route. Below we will introduce several common preparation methods in detail and analyze their applicable scenarios through comparison. <\/p>\n

Method 1: Cyclohexylamine methylation method<\/h3>\n

Principle<\/h4>\n

Cyclohexylamine methylation method is one of the classical preparation methods of DMCHA. This method produces the target product DMCHA by substitution reaction of cyclohexylamine with methylation reagents such as dimethyl sulfate or chloromethane. <\/p>\n

Step<\/h4>\n
    \n
  1. Raw material preparation<\/strong>: Mix cyclohexylamine and methylation reagent in a certain proportion. <\/li>\n
  2. Reaction conditions<\/strong>: Reaction is carried out under the action of a catalyst (such as sodium hydroxide or potassium hydroxide). <\/li>\n
  3. Post-treatment<\/strong>: After the reaction is completed, the DMCHA product is separated by distillation. <\/li>\n<\/ol>\n

    Pros and Disadvantages<\/h4>\n\n\n\n\n\n
    parameters<\/th>\nDescription<\/th>\n<\/tr>\n
    Pros<\/td>\nMaturity of process, simple operation, stable product quality<\/td>\n<\/tr>\n
    Disadvantages<\/td>\nTest using methylationAgents may bring certain safety risks<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Method 2: Hydrogenation and dehalogenation method<\/h3>\n

    Principle<\/h4>\n

    Hydrogenation and dehalogenation method uses dimethyl halide cyclohexylamine (such as dimethyl chlorocyclohexylamine) to carry out a hydrodehalogenation and dehalogenation reaction under the action of a catalyst to produce DMCHA. <\/p>\n

    Step<\/h4>\n
      \n
    1. Raw material preparation<\/strong>: Mix dimethyl halohexylamine with hydrogen. <\/li>\n
    2. Reaction conditions<\/strong>: Reaction is carried out under high temperature and high pressure in the presence of palladium-carbon catalyst. <\/li>\n
    3. Post-treatment<\/strong>: Purified DMCHA is obtained by filtration and distillation. <\/li>\n<\/ol>\n

      Pros and Disadvantages<\/h4>\n\n\n\n\n\n
      parameters<\/th>\nDescription<\/th>\n<\/tr>\n
      Pros<\/td>\nHigh reaction efficiency and fewer by-products<\/td>\n<\/tr>\n
      Disadvantages<\/td>\nHigh requirements for equipment and relatively high costs<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      Method 3: Biotransformation method<\/h3>\n

      Principle<\/h4>\n

      Bioconversion is an emerging green preparation method that uses microorganisms or enzymes to catalyze the conversion of specific precursor substances into DMCHA. <\/p>\n

      Step<\/h4>\n
        \n
      1. Strain Screening<\/strong>: Select microbial strains with high efficiency transformation capabilities. <\/li>\n
      2. Fermentation Culture<\/strong>: Under suitable culture conditions, let the microorganisms convert precursor substances into DMCHA. <\/li>\n
      3. Extraction and purification<\/strong>: Extract the target product by extraction and crystallization. <\/li>\n<\/ol>\n

        Pros and Disadvantages<\/h4>\n\n\n\n\n\n
        parameters<\/th>\nDescription<\/th>\n<\/tr>\n
        Pros<\/td>\nEnvironmentally friendly, low energy consumption, in line with the concept of green chemistry<\/td>\n<\/tr>\n
        Disadvantages<\/td>\nThe technical threshold is high, and the output is limited<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        Method Comparative Analysis<\/h3>\n\n\n\n\n\n\n
        Method<\/th>\nCost<\/th>\nEnvironmental<\/th>\nApplicable scenarios<\/th>\n<\/tr>\n
        Cyclohexylamine methylation method<\/td>\nMedium<\/td>\nGeneral<\/td>\nSmall-scale laboratory preparation<\/td>\n<\/tr>\n
        Hydrogenation and dehalogenation method<\/td>\nHigher<\/td>\nBetter<\/td>\nIndustrial mass production<\/td>\n<\/tr>\n
        Biotransformation method<\/td>\nLower<\/td>\nGood<\/td>\nGreen Chemistry Demonstration Project<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        From the above comparison, we can see that different preparation methods have their own advantages. In practical applications, the appropriate method can be selected according to specific needs. For example, cyclohexylamine methylation may be the first choice for small businesses that pursue low-costs; while for large-scale production companies that focus on environmental protection, the biotransformation law is more attractive. <\/p>\n

        \n

        DMCHA application areas: wide coverage from industry to life<\/h2>\n

        DMCHA, as a multifunctional organic compound, plays an irreplaceable and important role in many fields. Below we will discuss its typical applications in industrial production and daily life in detail. <\/p>\n

        Application 1: Epoxy resin curing agent<\/h3>\n

        Background<\/h4>\n

        Epoxy resin is a polymer material widely used in coatings, adhesives and composite materials. However, uncured epoxy resin has poor performance and cannot meet the actual use needs. Therefore, it is crucial to choose the right curing agent. <\/p>\n

        DMCHA’s Role<\/h4>\n

        DMCHA has become an ideal choice for epoxy resin curing agents due to its excellent alkalinity and solubility. It can effectively promote the cross-linking reaction between epoxy groups in epoxy resin and hardener, forming a strong and durable mesh structure. <\/p>\n

        Practical Cases<\/h4>\n

        In ship manufacturing, DMCHA is widely used in curing hull coatings, significantly improving the corrosion resistance and adhesion of the coating. In addition, in the electronics industry, DMCHA is also used to cure epoxy resin packaging materials to ensure the safe and reliable operation of electronic components. <\/p>\n

        Application 2: Medical Intermediate<\/h3>\n

        Background<\/h4>\n

        The pharmaceutical industry has a growing demand for high-quality intermediates, and DMCHA has become a key intermediate in the synthesis of many drug due to its structural properties and chemical activity. <\/p>\n

        Typical Example<\/h4>\n

        DMCHA is used as a chiral inducer during the synthesis of the anti-tumor drug paclitaxel, helping to build complex chiral centers in drug molecules. In addition, in antibiotics andDMCHA also plays an important role in the production of antiviral drugs. <\/p>\n

        Application 3: Catalyst<\/h3>\n

        Background<\/h4>\n

        Catalys are the cornerstone of the modern chemical industry, and DMCHA, as an efficient basic catalyst, performs excellently in many organic reactions. <\/p>\n

        Typical Reaction<\/h4>\n
          \n
        1. Esterification reaction<\/strong>: DMCHA can accelerate the esterification reaction between carboxylic acid and alcohol, improve yield and selectivity. <\/li>\n
        2. Amidation reaction<\/strong>: In the amidation reaction, DMCHA helps to reduce the reaction activation energy and shorten the reaction time. <\/li>\n
        3. Polymerization<\/strong>: As an initiator of polymerization, DMCHA can accurately control the molecular weight distribution of the polymer. <\/li>\n<\/ol>\n

          Table summary: Main application areas of DMCHA<\/h3>\n\n\n\n\n\n\n
          Application Fields<\/th>\nMain Functions<\/th>\nTypical Examples<\/th>\n<\/tr>\n
          Epoxy resin curing<\/td>\nImprove curing efficiency<\/td>\nMarine coatings, electronic packaging materials<\/td>\n<\/tr>\n
          Medicine Intermediate<\/td>\nConstructing complex molecular structures<\/td>\nPaclitaxel and antibiotic synthesis<\/td>\n<\/tr>\n
          Catalyzer<\/td>\nPromote organic reactions<\/td>\nEsterification reaction, amidation reaction<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

          From the above analysis, we can see that DMCHA has an extremely wide range of applications and has penetrated into almost all aspects of modern industry and life. Whether it is high-end pharmaceutical research and development or basic building materials production, DMCHA contributes its own strength with its unique performance. <\/p>\n

          \n

          DMCHA from the perspective of green chemistry: opening a new chapter in new catalytic technology<\/h2>\n

          As the global call for sustainable development is getting higher and higher, green chemistry has become an important direction for the development of the chemical industry. As a star molecule in the field of green chemistry, DMCHA is promoting the development of new catalytic technologies through its unique advantages. <\/p>\n

          The core concept of green chemistry<\/h3>\n

          The core concepts of green chemistry can be summarized as “3R” principles: Reduce, Reuse, and Recycle. This means that during the chemical reaction, the use and emission of harmful substances should be minimized, resource utilization should be improved, and environmentally friendly production should be achieved. <\/p>\n

          DMCHA’s Green Advantages<\/h4>\n
            \n
          1. Low Toxicity<\/strong>: Compared with traditional organic amine compounds, DMCHA is less toxic, reducing the harm to operators and the environment. <\/li>\n
          2. High selectivity<\/strong>: DMCHA shows extremely high selectivity in catalytic reactions, which can significantly reduce the generation of by-products and improve the utilization rate of raw materials. <\/li>\n
          3. Renewable<\/strong>: Preparing DMCHA through bioconversion method can not only reduce the consumption of fossil energy, but also realize the resource utilization of waste. <\/li>\n<\/ol>\n

            Exploration of new catalytic technology<\/h3>\n

            From the perspective of green chemistry, DMCHA is being widely used in the research and development of new catalytic technologies. Here are a few typical examples:<\/p>\n

            1. Photocatalytic Technology<\/strong><\/h4>\n

            Photocatalysis technology uses photoenergy to drive chemical reactions, which are energy-saving and environmentally friendly. As a highly efficient photosensitizer, DMCHA can excite electron transitions under ultraviolet or visible light, thereby triggering a series of chemical reactions. For example, in wastewater treatment, DMCHA can synergize with titanium dioxide (TiO\u2082) catalyst to efficiently degrade organic pollutants. <\/p>\n

            2. Electrocatalytic technology<\/strong><\/h4>\n

            Electrocatalysis technology promotes chemical reactions through the action of electric fields, and has the advantages of simplicity of operation and strong controllability. DMCHA can be used as an electrolyte additive during electrocatalysis to improve the reaction environment on the electrode surface and improve current efficiency. In the field of fuel cells, DMCHA is used to optimize the performance of cathode catalysts, significantly improving the energy density of the battery. <\/p>\n

            3. Biocatalytic Technology<\/strong><\/h4>\n

            Biocatalysis technology uses enzymes or microorganisms to perform catalytic reactions, which are characterized by mild conditions and high selectivity. DMCHA can act as a cofactor in biocatalysis to enhance enzyme activity and stability. For example, in lipase-catalyzed transesterification reactions, DMCHA can significantly increase the reaction rate and conversion rate. <\/p>\n

            Looking forward<\/h3>\n

            DMCHA has a broad application prospect from the perspective of green chemistry. With the further exploration of the properties of DMCHA and the continuous innovation of technology by scientific researchers, we believe that it will show greater value in more fields. In the future, DMCHA may become a multifunctional “supercatalyst” and contribute to the sustainable development of human society. <\/p>\n

            \n

            Conclusion: DMCHA\u2014\u2014The “Green Messenger” of the chemical world<\/h2>\n

            From molecular structure to physical and chemical properties, from preparation methods to application fields, to new types of induced stimulation from the perspective of green chemistryWe have analyzed the magical compound of DMCHA in a comprehensive way. It is not only an important tool in the chemical industry, but also a loyal practitioner of the concept of green chemistry. In the future, DMCHA will continue to create a better life for mankind with its unique advantages. <\/p>\n

            As a famous saying goes, “The progress of science is not inspired by genius, but from down-to-earth research.” The story of DMCHA is a good portrayal of this truth. Let us look forward to the fact that under the leadership of DMCHA, the world of chemistry will usher in more surprising discoveries! <\/p>\n

            Extended reading:https:\/\/www.cyclohexylamine.net\/dabco-ne300-nnn-trimethyl-n-3-aminopropyl-bisaminoethyl-ether\/<\/a><\/br>
            Extended reading:            https:\/\/www.bdmaee.net\/sponge-foaming-catalyst-smp\/<\/a><\/br>
            Extended reading:            https:\/\/www.newtopchem.com\/archives\/817<\/a><\/br>
            Extended reading:            https:\/\/www.bdmaee.net\/niax-a-4-catalyst-momentive\/<\/a><\/br>
            Extended reading:            https:\/\/www.cyclohexylamine.net\/pc-amine-ma-190-amine-balance-catalyst\/<\/a><\/br>
            Extended reading:            https:\/\/www.newtopchem.com\/archives\/45084<\/a><\/br>
            Extended reading:            https:\/\/www.cyclohexylamine.net\/no-emission-amine-catalyst-amine-catalyst-dabco-ne600\/<\/a><\/br>
            Extended reading:            https:\/\/www.cyclohexylamine.net\/category\/product\/page\/4\/<\/a><\/br>
            Extended reading:            https:\/\/www.newtopchem.com\/archives\/43944<\/a><\/br>
            Extended reading:            https:\/\/www.newtopchem.com\/archives\/44475<\/a><\/br><\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"excerpt":{"rendered":"

            Dimethylcyclohexylamine (DMCHA): a new catalytic techno…<\/p>\n","protected":false,"gt_translate_keys":[{"key":"rendered","format":"html"}]},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[6],"tags":[17656],"gt_translate_keys":[{"key":"link","format":"url"}],"_links":{"self":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/56213"}],"collection":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/comments?post=56213"}],"version-history":[{"count":0,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/posts\/56213\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/media?parent=56213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/categories?post=56213"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.newtopchem.com\/wp-json\/wp\/v2\/tags?post=56213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}